Diagram shows the heart looking from the front of the patient

The two chambers at the top are the left and right atria, sometimes known as the receiving chambers as they act as reservoirs for their respective ventricles. The two chambers at the bottom are the left and right ventricles, sometimes known as the pumping chambers as they are responsible for pumping the blood to the lungs and the body. The top and bottom chambers on each side are linked by a valve, the Mitral Valve on the left side and the Tricuspid Valve on the right side, and the wall between the left and right sides of the heart is called the septum.

Blood returning from the body enters the right atrium by way of the superior and inferior vena cava, from where it passes to the right ventricle via the Tricuspid Valve. When the heart muscle contracts, the Tricuspid Valve closes, and the pressure in the right ventricle rises and forces open the pulmonary valve allowing blood to enter the lungs via the pulmonary artery.

The main arteries of the lungs branch into very many smaller vessels (much like the structure of a tree: trunk, branches, twigs), with much thinner walls which are able to take tree oxygen from the air in the airways of the lungs. The oxygenated blood then returns from the lungs in the four pulmonary veins and enters the left atrium.

From the left atrium it is passed via the Mitral Valve to the left ventricle. Again, when the heart muscle contracts, the Mitral Valve closes, and the pressure in the ventricle rises forcing open the Aortic valve which allows blood to flow into the Aorta, and from there in to the many vessels which supply the body with blood.

Thus it can be seen that the right side of the heart pumps blood to the lungs, which is a relatively easy task, whilst the left side has the more difficult task of pumping blood all around the body. As a result, the pressures in the left ventricle are generally about four times greater than that in the right ventricle, and the wall of the left ventricle is thicker than that of the right.

A congenital heart defect is an abnormality in the structure of the heart which is present from birth, often described as a 'hole in the heart'. There are many variations, ranging from fairly 'simple' defects to complex problems involving all four chambers of the heart. Two children with the same defect will not necessarily show the same symptoms, as the exact size and placing of the hole(s), width of arteries, etc. will vary, and will result in a different presentation in each child. Due to the high incidence of cardiac problems in children with Down's Syndrome, it it therefore recommended that all babies have an echocardiogram early in life, and any suspected abnormality is examined by a cardiologist who can make a complete diagnosis.

"Finding out that our new baby had Down's Syndrome came as a great shock because no one at the hospital had ever mentioned it, and we thought it only happened to women in their forties. Discovering that he also had a serious heart defect was much worse! There was nothing we could do about the Down's Syndrome, it was nobody's fault, least of all the baby's! It just happened and we had to accept it in the same way that we had to accept that we had another boy when we would have liked a girl. But being told he had a life threatening heart condition was awful, we were lost and bewildered by all the medical information. All we wanted was for our little boy to live, it didn't matter that he had Down's Syndrome, he was our son and we loved him."